- Receive personalized recommendations based on gene-drug-phenotype associations.
- Browse the state of the art pharmacogenomics knowledge on gene-drug-phenotype associations.
- Upload individual genotypes and receive a report on their phenotypes for all known pharmacogenes.
- Browse pharmacogenomics summary data on a set of genotypes.

Health Professional

Biomedical Researcher

Visitor
Explore
The explore service contains a collection of state of the art gene-drug interactions. The dataset contains also metabolizing status and related haplotype information with links to original content. The interactions might be either dosing guidelines (high confindence clinical guidelnes) or clinical annotation (minor or unvalidated guidelines). The dataset can be browsed and the recommendations are appeared as an expandable tree.
Translate
The translation service offers the ability to upload an individual's genotype profile in VCF format. This profile is matched with a collection with known variants that are associated with ADME reactions. The results is a set of drugs that according to the database, their efficacy, dosage or action might be different from the reference. These results are indicative and by no means substitute a doctor's, clinician's or other expert's medical opinion.
Events
- Kleanthi Lakiotaki, Evgenia Kartsaki, Alexandros Kanterakis, Theodora Katsila, George P. Patrinos and George Potamias. "ePGA: a web-based Information System for Translational Pharmacogenomics". PLoS ONE, 11(9), 1–17. article. http://doi.org/10.1371/journal.pone.0162801 .
- K. Lakiotaki, E. Kartsaki, A. Kanterakis, T. Katsila, G. Patrinos, G. Potamias, "ePGA: an integrated electronic Pharmacogenomics Assistant for Personalized Medicine", 49th European Human Genetics Conference (ESHG), June 6-9, 2015, Glasgow, Scotland, United Kingdom [poster]
- K. Lakiotaki, E. Kartsaki, A. Kanterakis, T. Katsila, G. P. Patrinos, G. Potamias,"Translating Pharmacogenomics for Personalised Medicine", 24th Meeting go the Population Approach Group in Europe (PAGE), June 2-5, 2015, Hersonissos, Crete, Greece [poster]
- George Potamias, Kleanthi Lakiotaki, Evgenia Kartsaki, Alexandros Kanterakis,"Towards Predictive Pharmacogenomics Translation Models, "Workshop on Statistical Methods for Omics Data Integration and Analysis", November 10-12, 2014, Heraklion, Crete, Greece [Presentation]
- G. Potamias, K. Lakiotaki, E. Kartsaki,A. Kanterakis, G. P. Patrinos, “Towards Electronic Pharmacogenomic Assistance and Translation Services”, 2nd Conference on Pharmaceutical Sciences, October, 9-11, 2014, Patras, Greece. [Poster]
- Kleanthi Lakiotaki, Evgenia Kartsaki, Alexandros Kanterakis, George P. Patrinos and George Potamias, "A pharmacogenomics dashboard of 1000 genomes project populations", Golden Helix Summer School, September, 11-15, 2014, Aegina Island, Greece [Presentation]
- Kleanthi Lakiotaki, Evgenia Kartsaki, Alexandros Kanterakis, George P. Patrinos and George Potamias, "Towards a Pharmacogenomics Information System for Personalized Medicine", Golden Helix Summer School, September, 11-15, 2014, Aegina Island, Greece [Presentation]
- K. Lakiotaki, E. Kartsaki, A. Kanterakis, G. P. Patrinos, G. Potamias, "Pharmacogenomics Profiles from 1,092 Human Genomes", Wellcome Trust conference "1000 Genomes Project and Beyond", 2014, 24-26 June, Churchill College, Cambridge [Poster]
- K. Lakiotaki, G. P. Patrinos, G. Potamias, "Information Technology meets Pharmacogenomics: Design Specifications of an Integrated Personalized Pharmacogenomics Information System", IEEE-EMBS International Conferences on Biomedical and Health Informatics (BHI) 2014, June 1-4, Valencia, Spain [Presentation]
- G. Potamias, Translating –omics: The Pharmacogenomics Dimension, e-Health forum, May 12-14, 2014 [Presentation]
- G. Potamias, K. Lakiotaki, T. Katsila, M. Michael Lee, S. Topouzis, D. N. Cooper, G. P. Patrinos, "Deciphering next-generation pharmacogenomics: An information technology perspective", Open Biology, 4: 140071, (2014) [Paper]
- 1. G. Potamias , eMoDiA: electronic Molecular Diagnostics Assistant. 10th scientific workshop in FORTH, July 2013 [Poster]
ID | Drug | Gene | Chromosome | Position* | Variant | Phenotype | Source |
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* Use - to query for a specific genomic range. For example: 1000000 - 2000000
ID | Drug | Gene | Haplotype | Variants | Chromosome | Position* | Variation |
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* Use - to query for a specific genomic range. For example: 1000000 - 2000000
Drug | Gene | Haplotype 1 | Haplotype 2 | Organization | Metabolizer Status | Source |
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Institute of Computer Science
Foundation for Research and Technology, Hellas
email: potamias@ics.forth.gr